She's a multi-platinum selling pop superstar and is recognised as the world's top-selling female recording artist of all time by the Guinness World Records.
And although she's still enjoying success at the top of the U.S. charts, Madonna looks set to obtain a less enticing record by the end of this week.
The Material Girl's new album is on schedule to set the record for the biggest second week sales drop in history.
They state it will fall from 359,000 copies in its first week of release to around 46,000 in its second week in shops.
The 53-year-old Queen of Pop scored the biggest selling debut album of 2012 in America when it was released last week.
MDNA sold an impressive 359,000 units, making it her eighth album to top the Billboard 200 albums chart.
But a report released after she landed at the top spot suggested Madonna had resorted to some trickery in a bid to secure a number one spot on the Billboard charts, as her album wasn't sold the typical way.
Her label, Interscope, and Live Nation, which owns Ticketmaster, combined her latest album with ticket sales to her upcoming concert tour.
For every ticket that was sold to one of her shows, buyers also received a copy of MDNA.
They had the option of downloading on iTunes for free or receiving a hard copy in the post.
It isn't yet known how many album sales were directly attributed to concert ticket purchases.